CATHER is a threading algorithm for template-based modeling. It uses an iterative algorithm to combine both sequential information and contact maps to improve the threading performance. For a submitted query protein sequence, the returned results include the predicted structure.


  • Provide the protein data (mandatory)
  • Input protein data below: the query sequence in FASTA format: example).
    Or upload the protein sequence file:

  • Other information (optional)
  • Emails: (Optional, where the results will be sent to)
    Job name: (Optional, your given name to this job)


  • Z Du, S Pan, Q Wu, Z Peng, J Yang, CATHER: a novel threading algorithm with predicted contacts, Bioinformatics, 36: 2119-2125 (2020).